Surgical Pathology Update: Diagnostic Pearls for the Practicing Pathologist 2018

This CME activity is primarily intended and designed to educate pathologists.

• Develop an approach to common morphologic patterns seen in soft tissue tumors.
• Discuss the ancillary diagnostic approach to difficult soft tissue tumors including immunohistochemistry, molecular, and genetic diagnostic tests.
• Describe the most important diagnostic clues and patterns seen in soft tissue tumors which lead to a specific diagnosis.
• Explain the controversies regarding diagnostic criteria for Barrett’s esophagus and Barrett’s-related dysplasia.
• Discuss the effects of contemporary therapy on the pathology and management of patients with inflammatory bowel disease.
• Describe the role of the pathologist in helping to manage patients with IBD-related dysplasia and neoplasia.
• Apply risk stratification criteria for the prognostication of gastrointestinal stromal tumors.
• Discuss and recognize the succinate dehydrogenase-deficient gastrointestinal stromal tumor and understand the clinical significance of this category of GIST.
• Describe the transcription factors most useful for the identification of primary site location in metastatic carcinomas.
• Discuss the diagnostic markers for distinguishing hepatocellular carcinoma from metastatic carcinomas to the liver.
• Apply immunohistochemical markers to determine the primary site for metastatic well-differentiated neuroendocrine tumor.
• Accurately render a diagnosis of non-invasive follicular thyroid neoplasms with papillary-like nuclear features and recognize its mimics.
• Identify tumors with progression to poorly differentiated or anaplastic thyroid carcinoma.
• Recognize the morphologic spectrum of adrenal cortical carcinoma.
• Describe the features helpful in establishing a malignant diagnosis of prostate cancer on needle biopsy.
• Review the morphologic features essential in distinguishing benign mimickers from bladder cancer.
• Recognize unusual variants of common renal tumors and become familiar with more recently described renal tumors.
• Appreciate the subtle histomorphologic features that can help to distinguish well-differentiated ductal adenocarcinoma from reactive changes in the pancreas.
• Appreciate the anatomic and histologic compartments of the ampulla and their significance in the versatility and subclassification of ampullary tumors.
• Acquire knowledge of new concepts, terminology and histologic grading of pancreatic neuroendocrine tumors.