Description
2025 Jason L. Hornick, M.D., Ph.D. Expert Series – Practical Soft Tissue Pathology
Contemporary, case-driven soft tissue pathology training built around a practical, pattern-based diagnostic workflow—focused on reducing uncertainty, avoiding pitfalls, and translating modern WHO-era classification into real sign-out decisions.
Pattern-Based Approach
IHC + Molecular Strategy
WHO Updates
Soft Tissue Pitfalls
Sarcoma-Focused
IHC + Molecular Strategy
WHO Updates
Soft Tissue Pitfalls
Sarcoma-Focused
Release date: September 15, 2025 • Delivery via Google Drive (unlimited access + downloadable files).
Important Note
Cutaneous Mesenchymal Tumors: What’s New? is flagged as a source-session playback error (DocmedED-side issue).
Program Overview
This series is designed for real-world soft tissue tumor diagnosis—starting from morphology and pattern recognition, then selecting the right immunohistochemistry and molecular tests to narrow differential diagnosis efficiently.
Emphasis is placed on diagnostic “disaster prevention,” common traps, and practical reporting alignment with modern classification updates.
Emphasis is placed on diagnostic “disaster prevention,” common traps, and practical reporting alignment with modern classification updates.
Who Should Enroll
- Practicing anatomic & surgical pathologists who sign out soft tissue specimens and want a sharper, safer workflow
- Pathology fellows, senior residents, and trainees preparing for boards and aiming to reduce diagnostic uncertainty
- Surgical pathology teams supporting multidisciplinary tumor boards who want cleaner clinicopathologic correlation
Learning Objectives
- Apply a pattern-based approach to the differential diagnosis of soft tissue tumors
- Discuss the differential diagnosis of cutaneous mesenchymal tumors
- Describe key features of pleomorphic soft tissue tumors
- Recognize histologic and genetic subtypes of gastrointestinal stromal tumors (GIST)
- Apply a pattern-based diagnostic approach to vascular and nerve sheath tumors
- Select and apply immunohistochemistry effectively for soft tissue tumor diagnosis
What You’ll Cover
Pattern-Based Diagnosis
From morphology to a disciplined differential—how to think fast without missing rare but critical entities.
IHC Selection That Actually Helps
Marker choice, sequencing, and interpretation strategies that prevent false confidence and wasted panels.
Molecular Testing Strategy
When genetics matter most: how to confirm subtypes and handle “look-alikes” with confidence.
High-Risk Pitfalls
Epithelioid, myxoid, pleomorphic, and round cell patterns—what gets missed and how to prevent disaster.
Entity-Focused Deep Dives
GIST, vascular tumors, nerve sheath tumors, and cutaneous mesenchymal lesions with practical sign-out cues.
WHO Updates → Practical Reporting
Translate new taxonomy and grading concepts into actionable diagnostic language for daily workflow.
Lecture Topics
- Mesenchymal Tumors of the Head and Neck: Clues and Pitfalls
- Cutaneous Mesenchymal Tumors: What’s New? (source-session error note)
- Gastrointestinal Mesenchymal Tumors: What Do We Need to Know?
- Nerve Sheath Tumors: Key Features and Problems
- Vascular Tumors: Vasoformative and Not So Much
- Epithelioid Tumors: Diagnostic Challenges and How to Prevent Disaster
- Myxoid Tumors of Skin and Soft Tissue: From Benign to Malignant
- Round Cell Sarcomas: Histologic Clues and Ancillary Testing
- Pleomorphic Sarcomas: It Is Easier Than You Think!
- Spindle Cell Tumors of Adults (Part I): Differential Diagnosis and Best Markers
- Spindle Cell Tumors of Adults (Part II): Differential Diagnosis and Best Markers
- Introduction to Soft Tissue Pathology: WHO Classification, Grading, and a Pattern-Based Approach
Access & Delivery
All materials are delivered via Google Drive with unlimited access and downloadable files for offline study.
Medicine.ac does not provide CME, CE, or credits of any kind.
Bundle & Save
Save 15% on Bundles
Get 15% off when purchasing two or more courses together. This bundle discount is permanent and unlimited.
Related Courses
| Course | Best For | Rating |
|---|---|---|
| USCAP Tips and Hints in Surgical Pathology 2026 | High-yield sign-out pearls and practical diagnostic decision points | ★★★★★ |
| Harvard 46th Annual Current Concepts in Surgical Pathology 2025 | Broad surgical pathology update to complement soft tissue depth | ★★★★★ |
| Elizabeth A. Montgomery – Gastrointestinal Pathology | GI pathology mastery that pairs well with GIST-focused learning | ★★★★☆ |
| Rhonda K. Yantiss, M.D. Expert Series – Tips and Tricks for GI Biopsy Intervention 2025 | Practical GI biopsy sign-out tools and high-yield pitfalls | ★★★★☆ |
| 2025 Surgical Pathology | General surgical pathology reinforcement for daily sign-out confidence | ★★★★☆ |
| Prometric Pathology QBank 2025 (Offline for Windows & Android) | Board-style questions to lock in patterns and differentials | ★★★★★ |
| BoardVitals Pathology QBank 2025 | Question-driven review for exam pacing and core breadth | ★★★★☆ |
| AMBOSS Pathology QBank 2025 (Interactive Offline) | Interactive learning + rapid reinforcement using a structured quiz flow | ★★★★☆ |
Frequently Asked Questions
Is this series practical for daily sign-out?
Yes. The curriculum is built around pattern recognition, realistic differentials, and “what to order next” logic (IHC and molecular testing) to improve daily workflow and reduce diagnostic uncertainty.
Does it cover IHC strategy and molecular confirmation?
Yes. Sessions emphasize practical marker selection, interpretation pitfalls, and when genetics matters most for subtype confirmation and report accuracy.
What about the “Cutaneous Mesenchymal Tumors: What’s New?” video warning?
That lecture is flagged as a source-session playback error (DocmedED-side).
How is access delivered?
All materials are delivered via Google Drive with unlimited access and downloadable files for offline study.
Are credits included?
No. Medicine.ac does not provide CME, CE, or credits of any kind.
Student & Physician Experiences
★★★★★
Surgical Pathologist (R.D.)
“The pattern-based structure is exactly how I want to think at the microscope. The IHC strategy sections saved me from over-ordering and improved confidence on tricky cases.”
★★★★★
Pathology Fellow (M.K.)
“High yield and very practical—especially the nerve sheath, vascular, and round cell sarcoma approaches. Great for boards and day-to-day sign-out.”
★★★★☆
General Pathologist (S.T.)
“Clear differentials and strong pitfalls coverage. I appreciated the practical guidance on when molecular confirmation changes the diagnosis or the report wording.”
