Memorial Sloan Kettering Cancer Center Approach to Gastrointestinal Premalignant and Malignant Disorders 2024

Early recognition and management of premalignant gastrointestinal disorders are important in the prevention and early detection of cancer. With advances in our understanding of the pathogenesis and natural history of premalignant and malignant GI disorders, treatment algorithms continue to evolve. Emerging endoscopic techniques also play an important role in the diagnosis and management of these patients.

This one-day course will focus on the approach to the management of gastrointestinal premalignant and malignant disorders. It will update the participant on the diagnosis, management, and surveillance of various disorders involving the luminal GI, liver, and pancreaticobiliary tracts. Topics will include medical, endoscopic, and surgical management of Barrett’s esophagus with dysplasia, gastric intestinal metaplasia, Helicobacter pylori, gastric carcinoids, ampullary adenomas, hilar biliary obstruction, pancreas cyst lesions, hepatocellular carcinoma, inflammatory bowel disease with dysplasia, immunotherapy related GI complications, large colon polyps, early age onset colon cancer, surveillance for individuals at high-risk for pancreas cancer, hereditary gastric cancer, chemoprevention for Lynch syndrome and familial adenomatous polyposis and GI surveillance for emerging genetic mutations.

Who Should Attend

This course is intended physicians and other healthcare professionals who care for patients with gastrointestinal, liver, and pancreaticobiliary disorders, including gastroenterologists, surgical oncologists, medical oncologists, clinical geneticists, genetic counselors, surgical pathologists, fellows, residents, physician assistants, nurse practitioners, and registered nurses.

1. Describe the management of Barrett’s esophagus with dysplasia
2. Discuss the role of endoscopic submucosal dissection for upper GI neoplasia/early malignancy
3. Review the management of gastric intestinal metaplasia, helicobacter pylori and carcinoids
4. Describe the endoscopic management of ampullary adenomas
5. Explain the approach to treating hilar biliary obstruction
6. Recognize management options for pancreas cyst lesions
7. Recall surveillance strategies for hepatocellular carcinoma
8. Determine the treatment of inflammatory bowel disease with dysplasia
9. Discuss the approach to managing immunotherapy-related GI complications
10. Examine the risk factors and surveillance strategies for early age onset colon cancer
11. Identify increased-risk populations to screen for pancreas cancer
12. Evaluate innovative endoscopic techniques for treating large colon polyps
13. Describe the approach to management of hereditary gastric cancer
14. Apply GI surveillance strategies for emerging genetic mutations
15. Discuss chemoprevention for Lynch syndrome and familial adenomatous polyposis